What is neuropathic pain?
Neuropathic pain is caused by injury or disease affecting the somatosensory system. When the injury or dysfunction is located in the central nervous system, we call it central pain.
Neuropathic pain is characterised by its continuous character, irrespective of the physical load. Patients complain of burning, electric shock-like pain, with pain paroxysms accompanied by dysesthesia, and paresthesia.
The pathophysiological mechanism of neuropathic pain differs fundamentally from nociceptive pain, and is based on phenomena such as an increasing number of n Na+-channels, ectopic stimuli, etc.
Therefore, pain medication also focuses on the specific mechanisms of neuropathic pain.