What is nociceptive pain?
Nociceptive pain is due to tissue damage (inflammation), whereby substances are released that stimulate nociceptors.
Typical of nociceptive pain is that patients have periods of little or no pain. Moreover, the pain is usually load-dependent.
During tissue damage, many substances are released, including prostaglandins, which in particular stimulate nociceptors. NSAIDs and paracetamol intervene in the case of these released prostagladines, leading to pain reduction.